One blood test. One number. Clarity into MS disease activity, grounded in biology. So providers and patients can make data-backed decisions together.
29,000+
Scores delivered
500+
Prescribers
20,000+
Patients already empowered
Today's standard of care shows damage already done. The Octave Multiple Sclerosis Disease Activity (MSDA) Test reveals active disease biology, giving providers and patients the objective insights to adjust MS therapy with confidence - together.
Clinically validated
Backed by published research, the MSDA Test measures 18 biomarkers to detect MS disease activity and inform real-world care decisions.
Clarity at a glance
One simple number (1-10) gives providers and patients a clear read on current disease activity and tracking it over time helps catch changes early and confirm if the treatment is working.
Act sooner
Today’s standard of care measures damage already done. The MSDA Test reveals what’s happening now, so providers and patients can act sooner.
The MSDA Test combines 18 biomarkers, clinical context, and AI to deliver a personalized score from 1 to 10. Here’s how it works:
The MSDA Test measures the biology of MS disease activity in real time - detecting changes that may not yet appear in symptoms or on imaging.
Better data, better insight, better care. The MSDA Test supports clinical decision‑making by giving providers an objective measure of disease activity to interpret alongside symptoms, medical history, and imaging.
A single score is a snapshot. Tracking activity over time reveals trends, surfaces changes early, and informs whether the current care plan is working or needs revisiting.
MS is just the beginning. Octave is building the future of precision neurology, where no one faces a neurological condition without answers.
The mission: bring clarity and confidence to providers and patients navigating these diseases, with personalized insight across a range of clinical scenarios.
Detect disease activity before symptoms appear
Track disease activity over time to inform decisions
Guide therapy decisions with objective data
Support timely action when it matters most
Peer-reviewed research and real-world evidence from leading MS centers and clinical practices
SINGLE-TEST IMPACT
60%
Clinicians agreed one MSDA
result informed decisions
LONGITUDINAL IMPACT
69%
Clinicians agreed MSDA results
informed decisions over time
TREATMENT DECISIONS CHANGED
1 in 5
Documented decision changes
after MSDA testing
MULTI-PROTEIN PRECISION
18
Protein biomarkers
in one score
CLINICAL UTILITY
Real-world clinical utility of a multi-protein, blood-based biomarker assay for disease activity assessments in multiple sclerosis
Sanchez A, Sheng E, Eagleman S, et al. (2025)
CLINICAL VALIDATION
Clinical validation of a multi-protein, serum-based assay for disease activity assessments in multiple sclerosis
Chitnis T, Foley J, Ionete C, et al. (2023)
ANALYTICAL VALIDATION
Analytical validation of a multi-protein, serum-based assay for disease activity assessments in multiple sclerosis
Qureshi F, Hu W, Loh L, et al. (2023)
DISCOVERY
Inflammatory and neurodegenerative serum protein biomarkers increase sensitivity to detect clinical and radiographic disease activity in multiple sclerosis
Chitnis T, Qureshi F, Gehman VM, et al. (2024)
Peer-reviewed publications, poster abstracts, and scientific presentations from leading MS centers
CLIA Certified
Federal certification required
for all clinical labs
CAP Accredited
Gold-standard quality
accreditation
NY State CLEP
Approved under the nation’s most
stringent state lab oversight
Hear from patients and providers who’ve experienced the difference precision data has made for them
Patient
I’ve lived with MS for 22 years. I spent five of them in a wheelchair. I’m not interested in blind spots. The MRI tells you what happened. The MSDA Test tells you what to ask next. Now I test quarterly and bring the results to my neurologist. That’s the tool I never had before.
Patient
“My score went from 6.8 to 2.1 after switching medications. Seeing that drop gave me confidence that we made the right choice. I finally feel like I’m in control of my disease, not the other way around.”
Patient
My MRI scans have been stable for two years. My body tells a different story. The Octave MSDA Test helped bridge that gap - turning what I felt but couldn't prove into data I could bring to my neurologist. As a coach, I know you can’t improve what you can’t measure. As an MS patient and advocate, I believe every person living with this disease deserves tools that show the full picture. You are more than your MRI.
Neurologist
“My patients come to appointments more engaged and informed. The score gives us a shared language. They understand their disease activity, and it makes conversations about treatment changes much more collaborative and data-driven.”